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8arm PEG Maleimide (hexaglycerol)

产品代号:

8ARM-PEG-MAL

产品纯度:

≥ 90%

包装规格:

1g, 10g, 100g等(特殊包装需收取分装费用)

分子量:

10000Da, 20000 Da,40000 Da等

产品咨询:

科研客户小批量一键采购地址(小于5克)

  • 产品描述
  • 参考文献
  •   键凯科技提供高品质八臂聚乙二醇马来酰亚胺产品,产品取代率> 90%。

      键凯科技的8臂马来酰亚胺产品可交联制备PEG水凝胶产品。PEG水凝胶在医疗器械和再生医学方面尤其是在药物的缓释控释,2维和3维细胞培养以及伤口的缝合和愈合方面有非常广泛的应用。键凯的8臂PEG原料来通过三聚季戊四醇和乙氧基聚合而成,每个PEG链的乙氧基单元数目不是完全相同的。键凯的多臂PEG产品的分子量指的是各臂分子量的总和。

      键凯科技提供8ARM-MAL分子量10000Da, 20000 Da,40000 Da产品 1克和10克包装。

      键凯科技提供分装服务,需要收取分装费用,如果您需要分装为其他规格请与我们联系。

      键凯科技同时提供其他分子量的8ARM-MAL产品,如你需要请与我司[email protected]联系。

      键凯科技提供大批量生产产品及GMP级别产品,如需报价请与我们联系。

     

  •   References:

      1. Wang, J., et al., Multi-arm PEG-maleimide conjugation intermediate characterization and hydrolysis study by a selective HPLC method, Journal of Pharmaceutical and Biomedical Analysis, 2019, V. 164, P. 452-459.

      2. Dumont, C.M., et al., Aligned hydrogel tubes guide regeneration following spinal cord injury, Acta Biomaterialia, 2019.

      3. Verheyen, C.A. et al., Characterization of Polyethylene Glycol–Reinforced Alginate Microcapsules for Mechanically Stable Cell Immunoisolation, Macromolecular Materials and Engineering, 2019.

      4. Schweikle, M., et al., Stabilisation of amorphous calcium phosphate in polyethylene glycol hydrogels, Acta Biomaterialia, 2019.

      5. Buss, C.G., et al., Protease activity sensors noninvasively classify bacterial infections and antibiotic responses, EBioMedicine, 2018, V. 38, P. 248-256.

      6. Day, J.R., et al., The impact of functional groups of poly(ethylene glycol) macromers on the physical properties of photo-polymerized hydrogels and the local inflammatory response in the host, Acta Biomaterialia, 2018, V. 67, P. 42-52.

      6. Villa, C., et al., Effects of Composition of Alginate-Polyethylene Glycol Microcapsules and Transplant Site on Encapsulated Islet Graft Outcomes in Mice, Transplantation, 2017, 101(5), 1025-35.

      7. Darling, N.J., et al., Controlling the kinetics of thiol-maleimide Michael-type addition gelation kinetics for the generation of homogenous poly (ethylene glycol) hydrogels, Biomaterials, 2016.

      8. Li, Y., et al., Non-Covalent Photo-Patterning of Gelatin Matrices Using Caged Collagen Mimetic Peptides, Macromolecular Bioscience, 2015, 15(1), 52-62.

      9. Lu, H.D., et al., Injectable shear-thinning hydrogels engineered with a self-assembling Dock-and-Lock mechanism. Biomaterials, 2012, 33(7), p. 2145-2153.

      10.Stock, A.A., et al., Conformal Coating of Stem Cell-Derived Islets for β Cell Replacement in Type 1 Diabetes, Stem Cell Reports, 2020, 14(1), P. 91-104

           11.Kühn, S., et al., Tuning the network charge of biohybrid hydrogel matrices to modulate the release of SDF-1. Biological Chemistry. 2021.

           12.Ciciriello, AJ, et al., IL‐10 lentivirus‐laden hydrogel tubes increase spinal progenitor survival and neuronal differentiation after spinal cord injury. Biotechnology and Bioengineering. 2021.

           13.Widener, AE, et al., Guest–host interlinked PEG-MAL granular hydrogels as an engineered cellular microenvironment. Biomaterials Science. 2021, 9(7):2480-93.

          14.Bekdemir, A., et al., Ionic Liquid‐Mediated Transdermal Delivery of Thrombosis‐Detecting Nanosensors. Advanced Healthcare Materials. 2022.

          15.Zhang H., et al., Reprogramming of Activated Pancreatic Stellate Cells via Mechanical Modulation of Transmembrane Force-sensitive N-cadherin Receptor. Journal of Molecular Biology. 2023; 435(1):167819.

          16.Brown, T., et al., Design and development of microformulations for rapid release of small molecules and oligonucleotides, European Journal of Pharmaceutical Sciences, 188, 2023.

          17.Wan, W., et l., TGF-β1 promotes osteogenesis of mesenchymal stem cells via integrin mediated mechanical positive autoregulation, iScience, 2024, v. 27, I7. Keywords: Mechanobiology; Biological sciences; Cell biology; Mathematical biosciences; 8-arm PEG maleimide; 8-arm PEG thiol 

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