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键凯科技的八臂聚乙二醇羧酸产品可交联制备PEG水凝胶产品。PEG水凝胶在医疗器械和再生医学方面尤其是在药物的缓释控释,2维和3维细胞培养以及伤口的缝合和愈合方面有非常广泛的应用。键凯的8臂PEG原料来通过三聚季戊四醇和乙氧基聚合而成,每个PEG链的乙氧基单元数目不是完全相同的。键凯的多臂PEG产品的分子量指的是各臂分子量的总和。
键凯科技提供8ARM-CM分子量10000Da, 20000 Da,40000 Da产品 1克和10克包装。
键凯科技提供分装服务,需要收取分装费用,如果您需要分装为其他规格请与我们联系。
键凯科技同时提供其他分子量的8ARM-CM产品,如你需要请与我司[email protected]联系。
键凯科技提供大批量生产产品及GMP级别产品,如需报价请与我们联系。
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References:
1. Li, C., et al., An efficient prodrug-based nanoscale delivery platform constructed by water soluble eight-arm-polyethylene glycol-diosgenin conjugate, Materials Science and Engineering: C, 2019, 98, 153-60.
2. Dai, L., et al., Injectable and thermosensitive supramolecular hydrogels by inclusion complexation between binary-drug loaded micelles and α-cyclodextrin, Materials Science and Engineering: C, 2017.
3. Maisonneuve, B. G. C., et al., Effects of Synthetic Biomacromolecule Addition on the Flow Behavior of Concentrated Mesenchymal Cell Suspensions, Biomacromolecules, 2015, 16(1), 275-283.
4. Liu, Ke-Feng, et al., Design, synthesis and in vivo antitumor efficacy of novel eight-arm-polyethylene glycol–pterostilbene prodrugs, RSC Adv., 2015, 5, 51592-51599.
5. Dai, L., et al., Novel Multiarm Polyethylene glycol-Dihydroartemisinin Conjugates Enhancing Therapeutic Efficacy in Non-Small-Cell Lung Cancer. Sci. Rep., 2014, 4.
6. Rica, R., et al., Nanoparticle Growth via Concentration Gradients Generated by Enzyme Nanopatterns. Adv. Funct. Mater., 2014, 24: 3692–3698.
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