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　　Y型聚乙二醇马来酰亚胺是能在PH=5-6的条件下与巯基进行反应的具有Y分支的聚乙二醇衍生物。键凯产品Y分支衍生物是自主研发的Y型结构，由于具有独特的空间结构使他们比线性聚乙二醇衍生物更具有选择性。

　　键凯科技提供分装服务，需要收取分装费用，如果您需要分装为其他规格请与我们联系。

　　键凯科技同时提供其他分子量的Y型衍生物产品，如你需要请与我司[email protected]联系。

　　键凯科技提供大批量生产产品及GMP级别产品，如需报价请与我们联系。
　　References:

　　1. Li, H., et al., Dual MMP7-Proximity-Activated and Folate Receptor-Targeted Nanoparticles for siRNA Delivery, Biomacromolecules, 2015, 16 (1), p. 192–201.

　　2. Yu, W., et al., PEGylated recombinant human interferon-ω as a long-acting antiviral agent: Structure, antiviral activity and pharmacokinetics. Antiviral Research, 2014, 108, p. 142-147.

　　3. Fang, L., et al., Rational design, preparation, and characterization of a therapeutic enzyme mutant with improved stability and function for cocaine detoxification. ACS chemical biology, 2014, 9(8), 1764-72.

　　4. Fang, L., Computational Modeling, Design, And Characterization Of Cocainemetabolizing Enzymes For Anticocaine Medication, UKY, 2013, 39.

　　5. Resch, G., P. Moreillon, and V.A. Fischetti, PEGylating a bacteriophage endolysin inhibits its bactericidal activity. AMB Express, 2011, 1(29), p. 1-5.

　　6. Narasimhan, D., et al., Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time, Mol Pharmacol, 2011, 80:1056–1065.

　　7. Park, J.-B., et al., PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity, Journal of Controlled Release, 2010, 142(2), p. 174-179.